InsightRP2

Retinitis pigmentosa (RP) refers to a group of hereditary retinal diseases characterized by progressive degeneration, particularly of the photoreceptors. RP affects approximately 1 in 4,000 people worldwide and can be caused by changes in many different genes. Mutations in the RP2 gene are responsible for a significant proportion of X-linked retinitis pigmentosa (XLRP).

InsightRP2 is an innovative, multimodal project led by Prof. Bernd Wollnik. Researchers of the Wollnik Group are collaborating with experts in human genetics, ophthalmology, data science, cell biology, and gene therapy in Germany and Switzerland to investigate the genetic causes and disease mechanisms of RP2-associated retinal degeneration in order to develop new, targeted therapeutic strategies.